A 39-year-old female asked:
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i've had a few small hives after taking ibuprofen and aspirin. can i try aleve/naproxen? never had swelling, breathing issues and don't have asthma.

3 doctor answers
Dr. Arthur Balin
46 years experience Dermatology
Hives: People can have hypersensitivity reactions to every different type of medication or internally injested substance (including food). If you notice a reaction be sure to tell your doctor and avoid the substance most reactions can be stopped by avoidance of the offending agents. If important enough your doctor can use medication to suppress a reaction.
Answered on Mar 23, 2013
Dr. Nayla Mumneh
28 years experience Allergy and Immunology
No: If you react to an NSAID and aspirin, it is likely you will reactto all and the reaction may preogress and worsen with time, avoid all of them. Tylenol (acetaminophen) is ok to take.
Answered on Jun 10, 2014
Dr. Ronald Krauser
51 years experience Rheumatology
No: There is a cross-reactivity between Ibuprofen , asa and naproxen. If you get hives on one, the same will happen when trying the other meds. Rechallenging yourself with Naproxen may cause you to have a far worse allergic reaction next time.
Answered on Dec 27, 2014
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Dr. Richard Maughon
23 years experience Pain Management
since you had the problem with ibuprofen I would expect the same with naproxen - stick with tylenol it's not related ASA or ibuprofen
Sep 13, 2013

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