Rockville, MD
A 39-year-old female asked:

I've had a few small hives after taking ibuprofen and aspirin. can i try aleve/naproxen? never had swelling, breathing issues and don't have asthma.

3 doctor answers8 doctors weighed in
Dr. Arthur Balin
Dermatology 49 years experience
Hives: People can have hypersensitivity reactions to every different type of medication or internally injested substance (including food). If you notice a reaction be sure to tell your doctor and avoid the substance most reactions can be stopped by avoidance of the offending agents. If important enough your doctor can use medication to suppress a reaction.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Nayla Mumneh
Allergy and Immunology 31 years experience
No: If you react to an NSAID and aspirin, it is likely you will reactto all and the reaction may preogress and worsen with time, avoid all of them. Tylenol (acetaminophen) is ok to take.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ronald Krauser
A Verified Doctoranswered
Rheumatology 54 years experience
No: There is a cross-reactivity between Ibuprofen , asa and naproxen. If you get hives on one, the same will happen when trying the other meds. Rechallenging yourself with Naproxen may cause you to have a far worse allergic reaction next time.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Richard Maughon
Pain Management 26 years experience
since you had the problem with ibuprofen I would expect the same with naproxen - stick with tylenol it's not related ASA or ibuprofen
Sep 13, 2013

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Last updated Dec 27, 2014

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