A member asked:

Dose elavil (amitriptyline) effect gastric emptying in any way and at what doses

7 doctors weighed in across 3 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Yes: Elavil (amitriptyline) has strong anticholinergic properties, and can slow gastric emptying of solids. It can also slow your GI function farther down, leading to constipation. http://www.ncbi.nlm.nih.gov/pubmed/18803000.

Answered 11/28/2017

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Dr. Robert Olsen answered

Specializes in Psychiatry

Yes: Elavil (amitriptyline) blocks the chemicals that produce gastric emptying, acetylcholine. The dose is less important than the susceptibility of the person. If Elavil (amitriptyline) is otherwise the best medication foryou, there are other ways to stimulate gastric emptying. On the other hand, if you are using Elavil (amitriptyline) as an antidepressant or for its analgesic or sedative properties, there may be other options to consider.

Answered 6/1/2015

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Dr. Alan Ali answered

Specializes in Psychiatry

Elavil (amitriptyline): It slows gastric emptying due to its anticholinergic properties, usually at doses above 50mg.

Answered 6/1/2015

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