A member asked:

I was diagnosed with inflammatory breast carcinoma and the path report indicates poorly differeriated invasive. meaning?

6 doctors weighed in across 3 answers

Cell type: Pathologists describe what they see from a biopsy specimen. Inflammatory breast cancer can be an aggressive form of breast cancer. The biopsy describing invasive & poorly differentiated cells indicates likely an aggressive form of breast cancer. Your oncologist would have much more information to answer your questions more fully.

Answered 3/19/2013

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Dr. Devon Webster answered

Specializes in Medical Oncology

Aggressive: This means the cells look less "adult". As we develop, our cells take on functions (like making milk), and under the microscope they have an appearance that tells us what they do. So just by looking i can say "that is a breast cell that makes milk." cancer cells can get younger looking, so we can't tell by looking where they came from or what they do. That is a marker of a more aggressive cancer.

Answered 4/8/2013

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Aggressive tumor: Inflammatory bc causes redness and swelling of the breast mimicking and often mistaken for infection initially. They block the lymphatics in the skin. Usually arising from the lining duct cells, they are usually "poorly differentiated"- loosing much of their semblance to more normal looking cells and behave badly. They need aggressive mulitmodality treatments.

Answered 5/20/2013

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