A member asked:

How exactly does a lidocaine patch work?

3 doctors weighed in across 2 answers

See below: Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (na+) channels in the neuronal cell membrane that are responsible for signal propagation. When blocked the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential.

Answered 8/6/2017

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Absorption: The Lidocaine gets absorbed into the skin and acts at the local level to stop nerve conduction of the pain fibers in the region. Use only as directed and read the warnings!

Answered 12/19/2020

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