Histamine: Why opioids cause pruritis (itching) is partly because they cause a release of histamine which can make you feel itchy. It is a common side effect of these meds.
Answered 3/23/2013
5.2k views
Histamine release: Opiates can make you feel itchy secondary to histamine release, it is a normal side effect but you should consul with your doctor to make sure you are not getting a more serious allergic reaction.
Answered 7/1/2017
5.2k views
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