A member asked:

I just had a colonoscopy this morning and they found melanosis coli. i look up =abusive use with laxatives.i do not use laxatives. what else causes?

3 doctors weighed in across 2 answers
Dr. Eric Kaplan answered

Specializes in Colon and Rectal Surgery

Melanosis coli: If the diagnosis is correct is caused by cascara segrada an ingredient in many over the counter laxatives, softeners and herbal remedies. It causes deposits of pigment in the mucosal cells giving a black or leopard skin appearance to the colon lining instead of the natural pink appearance, it does not pose any medical risk but it does make diagnosis of colon pathology somewhat difficult.

Answered 3/6/2017

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Supplements: There are some iron-containing supplements that can cause the same appeareance. Some teas/supplements contain senna which can cause the melanosis appearance.

Answered 3/9/2020

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