A member asked:

Can you still vomit if your using metronidazole gel 0.75% and drink. are the symptoms different between the gel an pills?

A doctor has provided 1 answer
Dr. Marybeth Lambe answered

Specializes in Travel Medicine

Yes: Though level is lower, some gel is absorbed into the blood & a cross reaction between alcohol and Metronidazole can occur. 2 theories on this reaction which cause you to vomit, have headache, etc. 1) Disulfiram reaction -an old drug used to block alcohol processing & make alcoholics wish to avoid liquor. 2) possible central serotonin excess triggered causing equally awful side effects. Avoid booze.

Answered 9/29/2017

5.2k views

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