Why does nose itch after taking pain pills?

Side effect: This is a common side effect of narcotics.

Nose itch: Nose itch is a common side effect of opiate medications (pain pills). In some cases it can be the harbinger of an allergy, in which case it will gradually get worse every time with other symptoms appearing, or, more commonly, it is just an intolerance, a minor nuisance that comes with taking that kind of medication. The occurrence of hives with the itchy nose means you should never take it again.