NO: Is a trait, one abnormal gene, you need 2 abnormal genes to cause sickle cell disease. In extreme cases with low oxygen red cells can break when they change shape (sickle).
Answered 5/20/2013
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Maybe: Sickle cell trait can affect other organ systems. The kidneys seem to be the most often affected though not always. For that reason make sure to control your blood pressure well if that is a problem so as not to add to the kidney issue. It would not directly interact with the other conditions mentioned.
Answered 10/14/2014
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