A member asked:

Im taking 300mg of bupropion hydrochloride for depression , how will it mix with recreational drugs like cocaine or ketamine?

6 doctors weighed in across 2 answers

Bad Mixture: I am more concerned about mixing Cocaine and ketamine with your depression. In persons suffering from depression, recreational drug or alcohol use is not recommended. Bupropion and Cocaine lower a person's seizure threshold increasing one's risk of having a seizure. When using Cocaine and/or ketamine, one is less likely to make healthy lifestyle choices further worsening the depression.

Answered 10/23/2017

5.3k views

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Dr. Richard Pollard answered

Specializes in Anesthesiology

Badly: Cocaine and ketamine are not "recreational drugs". These drugs should not be taken at all, especially when you are on other drugs with effects on the central nervous system, such as bupropion.

Answered 4/24/2015

5.2k views

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