My son has epilepsy. he's been having minute to 2 minute long breakthrough seizures. had a 2 minute one today after med change. any idea why?

Medication Change: Hard to say for sure without having seen him, but if he recently had a medication change and now his seizure pattern is different, then the medication change would have to be at the top of my list of causes. Definitely need to talk/follow up with his physician.

Transitional events: The declining level of any anti-convulsant is a prime reason for recurrent seizures.If your kid had some level of benefit from the one you stopped & the other med had not reached protective levels yet, breakthrough would be a possibility. It is not uncommon to go through several meds before finding the one or combination that gives the most benefit.

Depends: Unlike an infection, which after culture, we know what antibiotics to prescribe, we do not have that specific a test. We learn about the adequacy of an anti seizure medication by its effect. It may take several days for any change in medication to reach a new blood level plateau, so it may take time for a change to be effective.