Can you take allergy medicine with hydrocodone?

It depends.: It depends on which allergy medicine it is -- talk to your doctor before mixing meds!

Maybe: I agree with dr. Juster; use caution when mixing narcotics with allergy meds. But, you need to know that hydrocodone is a natural stimulant leading to mast cells releasing histamine and causing itch. Not a true allergy, rather a side effect from the drug. Anti-itch medications can help but they can also worsen drowsiness. Maybe switching to something else would be best.