Hi. how come i feel more depressed when i take vitamins / minerals ? whats happening in my body and mind?

Hard to know: Without knowing exactly what you're taking, what your nutritional intake is like, and what conditions you might be dealing with (depression? Bipolar? Alcohol/substance abuse? Anxiety? Other medical issues? Other prescription meds?, etc) , we cannot answer this question. For an informed response, you would best work with your own physician -- and/or consult with an integrative medicine doctor.