A member asked:

When i take oral antihistamines i get hives over my entire body. is it possible to be allergic to antihistamines? what can be taken instead?

A doctor has provided 1 answer
Dr. Gary Moss answered

Unlikely: Each antihistamine is unique, so it is unlikely that you would be allergic to multiple antihistamines. I had one patient who had hives to an antihistamine, and it turned out to be an allergy to a dye. You should consult with someone familiar with these medications and medication reactions in general, such as an allergist.

Answered 8/23/2013

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