A member asked:

Igm 5054, asymtomatic cll stage 0, any suggestions?

11 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

IgM: If this is cll -as long as you are asymptomatic and no evidence of anemia, low platelet, or any other indication for treatment-then surveillance only will be the recommendation. However, I am just curious if you have numbness, tingling etc on your feet/hands? Need to make sure that it is truly a cll and not waldenstrom macroglobulinemia. I am sure your doctor already ruled waldenstom out, correct?

Answered 9/23/2017

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Dr. Ephraim Hochberg answered

Specializes in Medical Oncology

Very unusual: An IgM at this level would be very unusual with CLL. I would be suspicious that a bone marrow biopsy would reveal clonal plasma cells and a diagnosis of Waldenstroms. Very rarely patients have more than one lymphoid malignancy and this situation makes me suspicious. At this protein level I would check a viscosity and be seen frequently by a good malignant hematologist.

Answered 11/27/2017

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