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A member asked:

pregnant daughter in law was prescribed methylprednisolone for skin rash 4mg dose pack by her ob. what are the risks to the pregnanancy.

3 doctor answers3 doctors weighed in
Dr. Uzma Chaudhry
Internal Medicine 18 years experience
Catogory c: Methylprednisolone is a category c drug. There are adverse fetal effects in animals, but there are no controlled human studies or no animal or human studies. So basically the risk is unknown in humans.
Dr. Anthony Filly
Radiology 26 years experience
Not much: There is a loose and controversial association with cleft lip/palate but only with high doses, not a little dose pack for skin rash. I think she'll be fine.
Dr. James Ferguson
Pediatrics 46 years experience
Category C med: This medication has been studied in pregnancy & found to be relatively safe when used as directed. Pulsed use (med pack) provides little more than an increase of stress steroids produced naturally by human adrenal glands on a daily basis.

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Last updated Jun 28, 2014
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