A member asked:

What is the role of tnf-alpha in infertility? my wife has been asked to go for this test.

A doctor has provided 1 answer
Dr. Seth Derman answered

Specializes in Reproductive Endocrinology and Infertility

Not clear: Tnf Alpha is a growth factor secreted by natural killer cells a part of the immune system. The idea behind the linkage is that this immune reaction explains some cases of infertility. The concept is highly controversial and not widely accepted among reproductive medicine specialists.

Answered 6/24/2014

5.3k views

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