A 59-year-old female asked:
Can i take a sleep aid with valerian root with zoloft (sertraline)?
2 doctor answers • 4 doctors weighed in
A Verified Doctoranswered
20 years experience
Yes: Yes, that should be fine, i could not find any evidence of any drug interactions with the two meds.
Created for people with ongoing healthcare needs but benefits everyone.
5.3k viewsReviewed >2 years ago
Dr. Pamela Pappasanswered
Psychiatry 44 years experience
Slight issue: There are some in vitro and animal studies indicating that valerian could moderately inhibit one of the liver enzymes (cyp 3a4) necessary to process zoloft (sertraline). However, zoloft (sertraline) has multiple metabolic pathways so you should be okay if using less than 1000mg/day of valerian. Make sure your preparation is made from only the root, and not the whole plant.
Created for people with ongoing healthcare needs but benefits everyone.
5.3k viewsReviewed >2 years ago
Last updated Mar 6, 2018
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