Low, probably: If your granddad had hereditary hemochromatosis caused by homozygous mutations of the hfe gene, then your father has at least one mutation. Your mom may be a carrier - this is pretty common: about 1/9 people with a northern european background have 1 mutation. So your risk of inheriting 2 mutations may be about 3%. However, 75-90% of individuals with 2 mutations never get sick.
Answered 12/9/2013
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