Is it dangerous to mix tylenol (acetaminophen) sinus congestion with beer and ibuprofen?

Yes: There is no medication that should be mixed with alcohol. The tylenol (acetaminophen) sinus congestion already has Acetaminophen for pain, so adding Ibuprofen to it should be unnecessary. It worries me when people who are sick are concerned about whether they can drink while their sick, and it indicates a focus on alcohol that might mean trouble. Most sick people don't want to drink.