Unlikely: I assume that you are referring to oral or subcutaneous injected Methotrexate in doses used to treat rheumatic diseases such as rheumatoid arthritis. I have never read of or heard that Methotrexate can irritate the bladder lining.
Answered 6/28/2014
5.3k views
Not likely: Not likely, unless injected into the bladder.
Answered 2/2/2013
5.3k views
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