A member asked:

Can methotrexate irritate the bladder lining?

2 doctors weighed in across 2 answers

Unlikely: I assume that you are referring to oral or subcutaneous injected Methotrexate in doses used to treat rheumatic diseases such as rheumatoid arthritis. I have never read of or heard that Methotrexate can irritate the bladder lining.

Answered 6/28/2014

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Not likely: Not likely, unless injected into the bladder.

Answered 2/2/2013

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