A member asked:

Is cancer genetic?

10 doctors weighed in across 5 answers
Dr. Steve Martinez answered

Specializes in Breast Surgery

Some: Some cancers are genetic and run in families while others are sporadic and just randomly occur.

Answered 1/20/2014

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Only some: Many cancers occur sporadically. Breast cancer, ovarian cancer , familial colon adenomatosis polyposis , hereditary nonpolyposis colorectal cancer , multiple endocrine neoplasia ii, multiple endocrine neoplasia i, von hippel-lindau, ; li-fraumeni syndrome can be genetically linked.

Answered 3/12/2020

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Dr. Richard Roberts answered

Specializes in Pediatrics

Probably: We can identify many mutations which cause cancer or which predispose to cancer, such as BRCA 1 and 2, and provide invaluable susceptibility testing within a family. Now that we are getting down to recognizing the many dysfunctions which cause cancer, the mechanism in a non-classically genetic cancer may actually have an environmentally switched on genetic cause. There will likely be hundreds

Answered 10/11/2015

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Dr. Simon Kimm answered

Specializes in Urology

Yes and no.: Cancer is all genetic in that is arises from genetic changes that lead to the uncontrolled growth of cells. But these changes arise from a complex interplay between our inherited genes and our environmental exposures. Some cancers are completely inherited (vhl kidney tumors), some appear mostly environmental (smoking, hpv, radiation, diet), but most are a combination of both influences.

Answered 1/20/2014

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Cancer: Many cancers occur sporadically. Breast cancer, ovarian cancer, retinoblastoma, familial colon adenomatosis polyposis , hereditary nonpolyposis colorectal cancer, multiple endocrine neoplasia ii, multiple endocrine neoplasia i, cowden's syndrome, familial melanoma, neurofibromatosis, von hippel-lindau, ; li-fraumeni syndrome can be genetically linked.

Answered 1/21/2014

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