A member asked:

Is it safe to take benadryl (diphenhydramine) and zofran together?

6 doctors weighed in across 4 answers
Dr. Orrin Ailloni-Charas answered

Specializes in Anesthesiology

Yes: These drugs don't have any significant intersections when taken as prescribed.

Answered 2/6/2020

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Dr. Connie Topliff answered

Specializes in Family Medicine, Board Certified

Probably: But wonder why you need both. Also assume you are basically healthy and can safely take each of these drugs.

Answered 4/15/2018

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Probably: Fairly safe combo, depending on the dose.

Answered 12/19/2019

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Dr. Alan Ali answered

Specializes in Psychiatry

Benadryl/Zofran: Combo is safe!

Answered 2/6/2020

5.2k views

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