How is the brown recluse spider bite treated?

Clean & ice: The wound is cleaned and ice packs may be applied. An effected extremity is elevated. Non-steroidal anti-inflammatory medications may be used. Ulceration may sometimes be treated or prevented with dapsone. A tetanus shot may be required. Antibiotics may be necessary if the wound becomes infected. Large ulcerations could require debridment.

Observe: If there is good reason to believe that the spider bite is from a brown recluse, you will receive antibiotics and tetanus prophylaxis. You will use cold compresses and observe the bite at home for a few days for signs of progression such as blistering, pain, color change in skin around bite and fever. If these appear, you need to go back to the ER. Best wishes