Can anybody help my wife's problem, every time she sleep at our air condition room she is sick with ashma?

"catching astham": You don't "catch asthma" this way. If the a/c is making her sick every night she sleeps in the room with it on, then perhaps, you should have the a/c unit looked at. It might need cleaning.

Asthma: Perhaps cold air is one of her triggers. Perhaps you could agree on a slightly warmer room or she could sleep in another room where it is not so cold to see if there is any change in her symptoms.