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A member asked:
What are the chances of passing on a permutation of huntingtons to your children? 50/50 like if you actually had huntingtons?
A doctor has provided 1 answer
50/50: If one of your alleles of the hd gene is in the premutation range and the other is not, you have a 50:50 chance of passing it to an offspring. Interestingly, if the premutation allele is inherited from the father it has a higher probability of expanding the number of repeats to the disease causing range than if that same premutation allele was inherited from the mother.
Answered 1/21/2013
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