Frequent feeling of acid in throat it burns all day long nothing help not nexium (esomeprazole) or pepto not sure if its gerd or acid reflux have it all day long?

GERD and: Reflux are the same. Severe symptoms not relieved by medication require a consult and likely an egd (upper endoscopy).

GERD: It definitely sounds like gerd although i'm surprised the Nexium (esomeprazole) doesn't help. You would definitely be a person i would recommend an egd with a bravo ph probe placement. This is a great test to really see if what you are feeling is reflux and how bad it is. There are good surgical options if it is gerd and the medications don't work.

Maybe not GERD...: To expand on dr. Dugan's prior answer, evaluation is key to determining if your symptoms are reflux-related or not. Also, if reflux, is it acid or non-acid material that is involved? Sometimes, "sourbrash" (as you describe) may be due to pulmonary, ent, or dental issues. If unresponsive to therapeutic dosing of nexium, (esomeprazole) then start your evaluation with the gastroenterology specialist to determine rx.

LPR -should be in DD: The history is compatible with of Extra esophageal reflux- LPR- With throat burning and poor response to PPI..It is a variant of GERD with very little heartburn (also known as silent reflux).But with LPR, the sphincters don't work right. Stomach acid backs up into the back of your throat (pharynx) or voice box (larynx), or even into the NASAL airway's .managed with lifestyle changes. ...Continued