A member asked:

Hi doctor has given me buscopan for ibs was diagnosed today but i'm on clozapine will it react with it?

4 doctors weighed in across 2 answers

Yes it will: Buscopan has the active ingredient hyoscine which is anticholinergic. That means that the drug works against acetylcholine which is an important neurotransmitter for bowel and urinary motility, vision, and memory. Hence, there is an increased risk of anticholinergic side-effects, eg constipation, urinary retention, blurred vision, and confusion when taking the two together. I hope this helps.

Answered 1/9/2021

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Drug interactions: Agree with Dr. McCarron. UPer the Drugs.Com drug interaction checker, using these medications together "may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. "

Answered 1/9/2021

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