Is it dangerous to take ecstasy when i am taking bactrim (sulfamethoxazole and trimethoprim) antibiotics for a staff infection?

Yes, regardless: It is dangerous to take ecstacy period!

Hmm?: I am not aware of any established side effects of combining ecstasy and sulfa drugs. In general mixing medications is not a good idea. Also if you have a staph infection it might be because your immune system isn't working well. Could this be from all the partying? It is reasonable that ecstasy is a controlled substance. Consider stopping it and all drugs and alcohol to see how you do.