A member asked:

I was diagnosed adhd (inattentive) and take 50 vyvanse (lisdexamfetamine) in the morning and up to 40 adderall the rest the day. the crash is unbearable. what can i do?

14 doctors weighed in across 4 answers
Dr. Matthew Davis answered

Specializes in Child Psychiatry

Make changes...: Chose your stimulant. Don't combine stimulants. Longer acting agents tend to provide better coverage without sudden crashes. Given your need for such high doses i would expect a major issue is being neglected: regular restful sleep. Good sleep may allow for much lower doses of stimulant medication. Benadryl (diphenhydramine) 50mg may help improve sleep. A switch to another adhd med like Concerta may help as well.

Answered 10/13/2017

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Crashes: There several reasons for stimulants to be uneven in effectiveness, with sudden changes in blood levels, tolerance, metabolic clearance, etc. One remedy involves adding a small dose of Adderall or Dexedrine as the vyvanse (lisdexamfetamine) wears off. This can apply to shorter acting methylp forms as well.Extended release forms have not worked for everyone. Adding nonstimulants to " fill" gaps may help - bupropion.

Answered 10/13/2017

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Dr. Johanna Fricke answered

Specializes in Pediatrics - Developmental and Behavioral

Adjust doses or : Change medications. Vyvanse (lisdexamfetamine) 70 mg. In the am 2 hours before academic classes should last you 12--14 hrs. If not, try adding intuniv, the only fda-approved adjunct for treatment of adhd. You may want to take it at night, as it causes drowsiness for a few days after each weekly dose increase during titration from 1-4 mg. For optimal effect. Branded Concerta 72 mg + Intuniv also may work.

Answered 10/13/2017

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MEDICATION: Best to discuss medication with your Psychiatrist. If uncomfortable with your Dr. consult another for a second opinion. Have a physical exam by a Dr. to determine if you have a physical illness. Consult with a Clinical Psychologist for psychotherapy with ZOOM sessions. Fears and anxiety could be heightened due to the Covid-19 pandemic. Stay safe & hopeful to elevate your immune system.

Answered 12/13/2020

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