A member asked:

Is lung cancer hereditary?

15 doctors weighed in across 6 answers
Dr. Nathaniel Evans III answered

Specializes in Surgery - Thoracic

Rarely: The vast majority of lung cancer is thought to be caused by tobacco exposure. A small percentage of the lung cancer cases in non smokers are thought to be hereditary.

Answered 5/28/2017

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Unclear: Non or never smokers can develop lung cancer if they have a genetic mutation to such genes as egfr or eml4/alk fusion translocation. For more info: http://bit.Ly/ygfoko.

Answered 2/3/2014

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See below: There are no defined familial lung cancer syndromes; however, mutations in certain regions of the genome have higher incidence of lung cancer; some inherited changes in metabolic pathway genes may increase risk for carcinogensis from smoking.

Answered 3/24/2017

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In part: Heredity plays a role in most diseases, including lung cancer, however here are more important factors in the etiology of lung cancer, especially smoking. See this site for more information. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0004529/.

Answered 5/27/2015

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Dr. Raja Mudad answered

Specializes in Medical Oncology

Possible but not com: It is rare to have hereditary lung cancer, but not impossible. Several factors predispose to lung cancer, but the most significant one is controllable, like smoking do not smoke ever and you significantly reduce your chances of getting lung cancer.

Answered 6/6/2013

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Unclear: Non or never smokers can develop lung cancer if they have a genetic mutation to such genes as egfr or eml4/alk fusion translocation. For more info: http://bit.Ly/ygfoko.

Answered 7/7/2015

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