A member asked:

Can wellbutrin (bupropion) xl make u feel insane and angry?

3 doctors weighed in across 2 answers

Bupropion: Wellbutrin xl , a form of bupropion , is an antidepressant unlike many in use today. It does not work through the serotonin system the way prozac, (fluoxetine) celexa, or the other ssris. It is derived from a drug used as a diet pill, changed to treat depression. However, some people are sensitive to this chemical and get agitated, irritable and even psychotic, if predisposed. Talk to your md re: more options.

Answered 1/31/2019

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Get it checked: It is very important to let your prescribing provider know if you are feeling angry or crazy on wellbutrin, (bupropion) especially if accompanied by increased energy level, troubles sleeping and rapid thoughts.

Answered 1/31/2019

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