My neurologist prescribed prednisolone 10mg and my orth dr prescribed methylprednisolone 4 mg and lyrica (pregabalin) 50 mg . is it safe for me to take all this?

Doctor conference: Your doctors need to confer about the Prednisolone and Methylprednisolone so that they each realize what's being given to you. Being the patient, you can inform them also. If they talk, they may be able to mutually agree on your regimen and simplify it.

Limit Steroids: The Lyrica (pregabalin) is safe to add but you should not take Prednisolone and methylprednislone at the same time as both medication work in the same way.

Poor communication: Your situation is an excellent example when there is lack of communication between doctor and patient.