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A member asked:
Currently take amitryptaline 10 mg nightly for migraines is it safe to take nyquil for a cold or will there be an adverse interaction between the two?
2 doctor answers • 4 doctors weighed in

Dr. Donald McCarrenanswered
Neurology 38 years experience
Caution is advised: There is a drug to drug interaction between the 2 agents. The combination may increase the risk of CNS depression, psychomotor impairment, and anticholinergic adverse effects (additive effects). Hence, i would advise against the use of the 2 agents concomitantly.
Created for people with ongoing healthcare needs but benefits everyone.
5.4k viewsReviewed >2 years ago

Dr. Neetu Ahluwaliaanswered
Pain Management 22 years experience
It should be ok: Start with allow dose of nyquil if your concerned.
Created for people with ongoing healthcare needs but benefits everyone.
5.4k viewsAnswered >2 years ago
Last updated May 16, 2016
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