A member asked:

What is the definition or description of: lupus anticoagulant antibodies?

8 doctors weighed in across 3 answers
Dr. Thomas Klein answered

Specializes in Allergy and Immunology

See below: Lupus anticoagulant (la) is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. The disease name is a misnomer. La is actually a prothrombotic agent. The presence of la antibodies precipitates the formation of thrombi. The name derives from their properties in vitro, since in lab tests la causes an increase in clotting time.

Answered 3/31/2021

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Dr. Michael Dugan answered

Specializes in Hematology

Lupus anticoagualant: Is a tricky area. Patients with autoimmune diseases including lupus can present with a prolonged partial thromboplastin time (PTT) which would usually indicate an anticoagulant effect and risk for bleeding. Paradoxically, such individuals are at increased risk of clotting.

Answered 6/10/2014

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Risk factor for clot: These are antibodies that affect how blood clots, increasing risk of thrombi, pulmonary emboli, unsuccessful pregnancies and a series of other body system damage.

Answered 2/2/2013

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Related Questions

A member asked:

What is the definition or description of: lupus anticoagulant?

4 doctors weighed in across 2 answers