A member asked:

What is the definition or description of: angiotensin-1-converting enzyme?

A doctor has provided 1 answer
Dr. Michael Moran answered

Specializes in Cardiology

Angiotensin-1-converting enzyme converts angiotensi-1 to angiotensin-2, an extremely potent vasoconstrictor, leading to high bp. It is triggered by renin, produced in the kidneys due to low blood flow. The angiotensin converting enzyme inhibitors, or acei's are used to block this, but some still gets converted in the tissue, so we use angiotensin receptor blockers, or arb's.

Answered Dec 6, 2012

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