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A 28-year-old male asked:

What is the definition or description of: angiotensin-1-converting enzyme?

1 doctor answer1 doctor weighed in
Dr. Michael Moran
Cardiology 25 years experience
Major BP problems...: Angiotensin-1-converting enzyme converts angiotensi-1 to angiotensin-2, an extremely potent vasoconstrictor, leading to high bp. It is triggered by renin, produced in the kidneys due to low blood flow. The angiotensin converting enzyme inhibitors, or acei's are used to block this, but some still gets converted in the tissue, so we use angiotensin receptor blockers, or arb's.

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Last updated Dec 6, 2012

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