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A 28-year-old male asked:

what is the definition or description of: pernicious anemia?

3 doctor answers5 doctors weighed in
Dr. Derrick Lonsdale
Preventive Medicine 73 years experience
Vitamin deficiency: Pa is due te either vitamin B12 or folate (folic acid) deficiency. Originally it was found that the "intrinsic" factor (produced in the stomach) was missing and this is an essential element for the absorption of b12. Any cause of B12 or folate (folic acid) deficiency results in changes in the blood by which it can be recognized.
Dr. Steven Ginsberg
Hematology and Oncology 37 years experience
See below: Pernicious anemia results from the inability to absorb vitamin B12 normally due to a lack of intrinsic factor, a substance required for adequate B12 absorption. This leads to macrocytic anemia; large red blood cells. It is no longer "pernicious" as it is easily treated with either large doses of oral vitamin B12 , or injectable vitamin b12.
Dr. Julio Hajdenberg
Hematology and Oncology 31 years experience
Due 2 B12 deficiency: It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily treatable with replacement therapy.

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A 31-year-old member asked:

Are there other tests to determine sickle cell anemia risk if my husband is away serving in the military?

2 doctor answers3 doctors weighed in
Dr. Jeff Livingston
Obstetrics and Gynecology 22 years experience
Yes: The first step is testing you for sickle cell carrier status. If not a carrier then no further testing needs to be done. If you are a carrier then the next step is check the father of the baby. If he is unavailable you could have his parents tested. If neither are a carrier then the father can not be a carrier either. If they are carriers then the fathers chances are 50% he is also.
A 22-year-old member asked:

Can childbirth cause anemia?

2 doctor answers5 doctors weighed in
Dr. Albert Pizzo
Family Medicine 60 years experience
Anemia: Yes. The fetus during pregnancy draws many substances from the mother, one of which is iron. If the mother has a poor intake of iron, then she is prone to iron deficience anemia. Also if the mother has a large amount of blood loss during delivery, this can cause anemia.
A 21-year-old member asked:

What causes anemia in people with diabetes?

2 doctor answers5 doctors weighed in
Dr. Zouhdi Hajjaj
Internal Medicine 23 years experience
Kidney disease: Diabetes, especially if not controlled, will negatively affect kidney function, notably with respect to that organ's vital function in stimulating blood cell production. The kidneys do so by secreting a hormone that leads to red cell production.
Dr. Ritesh Rathore
Hematology and Oncology 30 years experience
additonally inflammatory compnonent of poorly contolled diabetes can reduce new blood cell production and cause anemia of chronic disease.
Feb 8, 2012
A 21-year-old member asked:

What are cyanate and thiocyanate? Can they be used to treat sickle cell anemia?

2 doctor answers4 doctors weighed in
Dr. Pedro Hernandez
Geriatrics 40 years experience
Ask ur Hematologist: Dietary cyanate, from foods containing cyanide derivatives, has been used as a treatment for sickle- cell anemia. In the laboratory, cyanate and thiocyanate irreversibly inhibit sickling of red blood cells drawn from sickle cell anemia patients. However, the cyanate would have to be administered to the patient for a lifetime, as each new red blood cell created must be prevented from sickling.
A 21-year-old member asked:

What are the different types of sickle cell anemia?

2 doctor answers6 doctors weighed in
Dr. Pedro Hernandez
Geriatrics 40 years experience
Types os SIckle Cell: From nih, division of blood diseases and resources: sickle cell disease-ss: 65% of us patients; genotype s/s sickle cell disease-sc: 25% of us patients; genotype s/c sickle cell disease-s beta + thalassemia: 8% of us patients; genotype betas/ beta + thalassemia sickle cell disease-s beta 0 thalassemia: 2% of us patients; genotype betas/ beta 0 thalassemia.

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Last updated Apr 5, 2018
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