A member asked:

What's the difference between hyaluronic acid and cortisone injections?

4 doctors weighed in across 2 answers

Big differences: Cortisone injections are performed to decrease joint inflammation. Injections with hyaluronic acid derivatives have a number of known and some unexplained actions on the joint. The hyaluronic acid derivatives increase lubrication, and change how the lining of the knee functions. Cortisone is usually one injection, hyaluronic acid is 3 or more injections.

Answered 2/25/2016

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Dr. Lauren Romeo answered

Specializes in Wound Care

A lot!: Hyaluronic acid is a substance derived from animal skin and joints..And is found in our own bodies. Injectable cortisone is a drug. We make our own cortisone but it is not the same. There are many side effects to cortisone. Ask your pharmacist to give you information on each.

Answered 9/10/2019

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