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A 39-year-old member asked:

i accidentally overdosed on loratadine. what can i do?

2 doctor answers5 doctors weighed in
Dr. Michael P Vaughn
Allergy and Immunology 34 years experience
Nothing: Claritin (loratadine) and most other nonsedating third generation antihistamines are very safe. The initial studies for Claritin (loratadine) were done at 40 mg (4 times the currently recommended dose). If a physical symptom is experienced after using any medication at an excessively high dose, the best resource is the "poison control" center. They are available 24/7 by calling 1-800-poison1.
Dr. Jack Mutnick
Allergy and Immunology 17 years experience
Overdosed: If you overdosed, call 911 immediately and get to the emergency room. If you simply took two or three pills, the main side effect is drowsiness. Do not drink alcohol with loratadine.

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A 21-year-old member asked:

I've developed a high tolerance for a drug. Does this mean i'm less likely to overdose?

2 doctor answers5 doctors weighed in
Dr. James Fox
Psychiatry 14 years experience
No: It may mean you are more likely to overdose since it will require more drug to achieve the same desired effect. The best way to avoid overdose is not to take the drug in the first place. Believing one is safe from overdosing is the fastest way to end up overdosing.
CA
A 28-year-old member asked:

Which drugs interfere with alavert (loratadine)?

3 doctor answers3 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
A few drugs: Amiodarone and darunavir. One used for cardiac arrhythmias and the other for HIV infections. Both can cause loratidine levels to increase.
A 25-year-old member asked:

For how long does Claritin (loratadine) stay in your system?

3 doctor answers7 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
One day: Claritin (loratadine) 10 mg pill is dosed once daily. That's because it's effect will last about 24 hours, after that it's antihistamine effect wanes. However, Claritin is metabolized by the liver into another active compound called desloratadine, so the antihistamine effect can last a while. This is why most allergists have patients stop their Claritin a number of days before skin testing them.
A 50-year-old member asked:

How much time does it take Claritin (loratadine) to work?

2 doctor answers14 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
Within 1-2 hrs: Claritin (loratadine) is well-absorbed from the gastrointestinal tract and its effect is often felt within 1-2 hours. Claritin is metabolized in the liver into Desloratadine (the main ingredient in clarinex) which can stay in your system for many hours, allowing these antihistamines to be dosed once daily.
A 50-year-old member asked:

Is it possible for doctors to accidentally overdose someone on radiation therapy?

3 doctor answers6 doctors weighed in
Dr. Reza Shirazi
Radiation Oncology 20 years experience
Yes: But it is extremely rare, there is lots of quality assurance and double and triple checking to assure correct dosing.

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Last updated Sep 28, 2020

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