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A member asked:
How long does it take naloxone to get out of my system?
6 doctors weighed in across 2 answers
Nifty Naloxone: Naloxone, or Narcan (naloxone) is intended to reverse narcotic overdose and is usually given in the vein, muscle or breathing tube (in emergencies). It has a very rapid onset of action but a short life in the body. It's half life is 64 minutes, which means in approximately 4 hours it is completely out of the body primarily through the kidneys. Diminished kidney function could prolong the drug effect.
Answered 6/1/2019
6.2k views
20-30 minutes: Naloxone is short acting. When given intravenously, it lasts 20-30 minutes; if it is given by nasal spray, takes a little longer to kick in (minutes instead of seconds) but lasts a little longer, perhaps up to an hour. Since many opiates are longer acting than that (esp Methadone and oxycontin), an od can recur after the Naloxone wears off. Naloxone is not tested for in most drug testing.
Answered 7/10/2018
5.5k views
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