A member asked:

How is cf inherited?

3 doctors weighed in across 2 answers

From both parents: CF is an autosomal recessive disorder meaning the infant must inherit a mutated or abnormal copy of the CF gene from both the mother and the father. If both parents are carriers of a CF mutation, the odds of the infant having CF are 1 out of 4 or 25% for every pregnancy.

Answered 1/15/2015

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From both parents: Parents each pass half their ladder like dna to baby, the dna divides lengthwise with half a rung/parent. If half a rung is a dominent gene, the parent has the problem & passes it. If it takes 1 half from each parent to pass, it is a recessive problem & parents are not affected.Cf is carried in an estimated 1/20 unaffected people. A carrier couple can produce carrier/affected or normal kids.

Answered 8/19/2011

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