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A 44-year-old member asked:

Is it safe for me to eat grapefruits while i'm taking sertraline and hydrocodone?

2 doctor answers5 doctors weighed in
Dr. Matt Pflieger
Family Medicine 40 years experience
No: Grapefruit can affect the breakdown of sertaline (zoloft) and could make it ineffective.
Dr. Pamela Pappas
Psychiatry 42 years experience
No: Grapefruit and grapefruit juice may decrease your body's processing of sertraline and hydrocodone. This means their levels could build up in your body and intensify side effects. Do not combine these medications with grapefruit. Other citrus fruits appear to be safe, though. http://www.medicinenet.com/script/main/art.asp?articlekey=14760.

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Last updated May 7, 2016

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