You : You are correct about the hereditary nature of factor 5 leiden. People can be homozygous (two chromosomes) or heterozygous (one chromosome) for the condition, and both the risk of clotting and the treatment differ depending upon the genetic pattern. In general, treatment is limited to blood thinners, but the type, the level of therapy, and the duration of therapy all depend on the genetics and the pattern of clot development. It can be a tough disease to treat, so if your husband has not seen a hematologist, he should. If you are thinking about starting a family, you might also want to meet with a genetic counselor to discuss the risk of passing this condition on to your kids. If his blood clots are new, and if he was not on blood thinners when they formed, there might be a role for dissolving them with a medication called tpa (alteplase). You might want to ask his doctor about that option.
Answered 10/3/2016
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