A member asked:

What is the difference between stage and grade for brain cancer?

4 doctors weighed in across 2 answers

Grade is key.: Brain tumors are rated by the world health organization grade, with higher grades generally being more aggressive. Stage is a terminology used in cancers outside of the brain, which describe how much a cancer has spread all over the body. Because brain tumors/cancers generally do not spread all over the body, we rarely use "staging" with primary brain tumors.

Answered 7/20/2012

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Primary brain: Tumors in adults never metastasize, and the grade determines prognosis, time of survival, or time to recurrence. The grade + stage, but commonly low grade is stage i, ii including astrocytoma, oligoastrocytoma. Anaplastic astro: grade 3; glioblastoma, is stage iv.

Answered 9/28/2016

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