A member asked:

What pain medicine is safe to take with plavix (clopidogrel)?

5 doctors weighed in across 3 answers
Dr. Jay Bradley answered

Specializes in Cornea, Cataract, & Refractive (LASIK & PRK) Surgery

Any pain med: Unless you have some serious bleeding disorder, severe liver ir kidney disease, or allergy, any pain medication can be used in conjunction with plavix (clopidogrel).

Answered 6/14/2019

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Dr. Nassir Azimi answered

Specializes in Interventional Cardiology

Tylenol (acetaminophen): Acetaminophen/tylenol is safe to take with plavix (clopidogrel). Nsaids like Ibuprofen is risky as it can increase risk of bleeding particularly if taken repeatedly over days.

Answered 9/18/2019

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Avoid NSAIDs/Aspirin: Nonsteroidal-antiinflammatory drugs (nsaids-such as motrin/aleve) and aspirin-based analgesic can interact with Plavix (clopidogrel) and increases risk of bleeding/stomach and intestinal ulcers/performation etc..Otherwise narcotic pain killers (some mixed with tylenol) are ok to take while being on plavix (clopidogrel). Like all medicine, use the smallest effective dose for shortest duration possible. Consult doc. Good luck.

Answered 1/22/2020

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