A 44-year-old member asked:
Is prader willi syndrome hereditary?
1 doctor answer
Dr. Golder Wilson answered
Specializes in Clinical Genetics
Yes and no: Prader-willi syndrome involves early low tone with later overeating and obesity since the person is never full. It is genetic, with ~70% of cases having deletion (missing part) of chromosome 15 and the others having altered parental patterning (genomic imprinting). Although always due to a genetic change, it is rarely inherited and has a low recurrence risk for parents of an affected child.
Answered on Apr 12, 2015
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