A member asked:

What are some of the chemicals used in chemo to treat aml m4 my daughter was diagnosed with aml m4 but after chemo started had signs of aml m3?

4 doctors weighed in across 3 answers

Chemotherapy: Typical drugs used to treat m4 AML are Cytarabine and either Daunorubicin or idarubicin. There are other drugs that may be used.

Answered 6/25/2014

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Dr. James Ball answered

Specializes in Pediatric Hematology and Oncology

Chemo: Undoubtedly she was treated with cytatabine, Daunorubicin and etoposide. I have seen AML be of two morphological types (m4 and m5 or, in her case m3 and m4).

Answered 10/3/2016

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Dr. Matthew Fero answered

Specializes in Medical Oncology

The FAB type...: e.g. M4, M5, etc. is based on the microscopic appearance of the leukemia cells. Usually the FAB class is not so important for choosing the drug treatment. M3 is different. A true M3 leukemia (aka acute promyelocytic leukemia) will also have a very specific gene mutation (PML/RARA) on molecular testing or cytogenetics. It is highly treatable, and responds to other drugs (esp. retinoic acid and ATO)

Answered 4/25/2016

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