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A member asked:
What are some of the chemicals used in chemo to treat aml m4 my daughter was diagnosed with aml m4 but after chemo started had signs of aml m3?
4 doctors weighed in across 3 answers
Chemotherapy: Typical drugs used to treat m4 AML are Cytarabine and either Daunorubicin or idarubicin. There are other drugs that may be used.
Answered 6/25/2014
5.5k views
Chemo: Undoubtedly she was treated with cytatabine, Daunorubicin and etoposide. I have seen AML be of two morphological types (m4 and m5 or, in her case m3 and m4).
Answered 10/3/2016
5.5k views
The FAB type...: e.g. M4, M5, etc. is based on the microscopic appearance of the leukemia cells. Usually the FAB class is not so important for choosing the drug treatment. M3 is different. A true M3 leukemia (aka acute promyelocytic leukemia) will also have a very specific gene mutation (PML/RARA) on molecular testing or cytogenetics. It is highly treatable, and responds to other drugs (esp. retinoic acid and ATO)
Answered 4/25/2016
3k views
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