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A member asked:

M spike in.urinie protine alpha 2?

A doctor has provided 1 answer

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign.

Answered 11/20/2012

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