Can esophageal cancer spread to supraclavicular lymph nodes without causing any symptoms?

Sadly yes: Esophagus is a muscular tube that can stretch, so often no symptoms until it can't . Also has no outer membrane surrounding it so easier to spread outside the organ itself.

Unfortunately yes: Supraclavicular lymph node spread is possible with out symptoms from the primary tumor. Supraclavicular lymph node metastasis does not preclude treatment, but likely rules out surgery.

Yes: Esophageal cancer can go unnoticed for a while. I have seen patients present with very advanced disease without a long course of symptoms. Supraclavicular lymph nodes without a clear explanation need to be evaluated carefully. A number of tumors can spread to the supraclavicular nodes including lung, esophagus, stomach and ovarian cancers.

Yes: The symptom is the inability to swallow food or liquid comfortably. Esophageal cancer is generally circumferential, like a doughnut. The hole or the lumen becomes smaller as the cancer grows, making it difficult for food and then liquid to pass through. However, that hole can be as small as 6mm in diameter before symptoms appear. So esophageal ca often has no symptoms.