I've been taking wellbutrin (bupropion) for three weeks and have major constipation with pain when sitting and when i put pressure on the toilet. does this mean wellbutrin (bupropion) isn't working and does it go away after my body adjusts to it?

Side effect: It's a common side effect from antcholinergic meds use one or two stool softeners at nite & see doc if that doesn't take care of it.

No: Usually contstioationin this setting is from an inadequate amount of fiber and fluid in your diet. You should start with 6 grams of psyllium and an extra pint of water daily. Occassionally, drugs like wellbutrin (bupropion) can affect bowel motility. This is usually self limited.